Periostitis as the initial manifestation of systemic vasculitis

Oral contraceptive-related transverse sinus thrombosis as an initial manifestation of antiphospholipid syndrome in the absence of systemic lupus erythematosus

Hemophagocytic syndrome as the initial manifestation of systemic lupus erythematosus.

INTRODUCTION Hemophagocytic syndrome (HS) occurs in autoimmune diseases and belongs to the hemophagocytic lymphohistiocytosis group of diseases. This paper describes the features of 2 patients with systemic lupus erythematosus (SLE) who presented HS as the initial clinical manifestation. CLINICAL OBSERVATIONS Both patients had prolonged fever not associated to an infectious process and did no...

Embolic Stroke as the Initial Manifestation of Systemic Lupus Erythematosus

We present a case of a 21-year-old African-American female with no significant medical history, who presented to the emergency department with a one-week history of blurry and double vision. Ophthalmology evaluation revealed bilateral retinal artery occlusion. Further workup with imaging of the brain was consistent with an ischemic stroke. Hereditary hypercoagulable workup was unremarkable and ...

Persistent varicella as the initial manifestation of systemic lymphoma.

Varicella is a common benign childhood disease that often presents in adolescents and adults in a more severe form. We report a previously healthy 50-year-old man who developed multiple necrotic cutaneous ulcers associated with fever, asthenia and anorexia. Physical examination revealed few tense hemorrhagic vesicles on the trunk and necrotic cutaneous ulcers scattered over the entire cutaneous...

Lupus nephropathy as the initial manifestation of systemic lupus erythematosus.

The present report documents the occurrence of lupus nephropathy as the sole initial manifestation of systemic lupus erythematosus (SLE). Despite the absence of initial systemic signs characteristic of SLE, the diagnosis was confirmed on the basis of the renal histopathologic features and serological studies. Subsequent follow-up demonstrated systemic features of the disease in each of the four...